Linked Life Data

968444

Source:http://linkedlifedata.com/resource/pubmed/id/968444

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-11-21
pubmed:abstractText
Lipids of rat plasma and erythrocytes were analysed during hyperlipidaemic diet and clofibrate treatment. The diet increased the plasma cholesterol and phospholipid concentrations after 3 weeks' lipid feeding. Clofibrate in a dose of 200 mg/kg body weight did not inhibit the increase in plasma cholesterol and phospholipid contents, but significantly decreased the concentration of plasma triglycerides. The lipid diet slightly increased the erythrocyte cholesterol and phospholipid concentrations without affecting the red cell morphology or reticulocytosis. After 1 week's treatment, clofibrate in a dose of 200 mg/kg body weight caused a 2-fold increase in the cholesterol content and a rise in the cholesterol-phospholipid ratio of red blood cells of rats fed the hyperlipidaemic diet. These results suggest that the erythrocyte cell membrane can increase its cholesterol content and possibly play a role in cholesterol transport.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0036-553X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
117-22
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Effect of hyperlipidaemic diet and clofibrate treatment on rat erythrocyte lipids.
pubmed:publicationType
Journal Article