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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1998-8-11
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pubmed:abstractText |
Integrins are heterodimeric cell surface molecules involved in cell-cell and cell-matrix interactions. Adenoviral entry into human cells has been shown to be dependent on integrins alpha v beta 5 and alpha v beta 3 that promote viral internalisation. We studied the distribution of integrins alpha v beta 5, alpha v beta 3 and the alpha v chain in normal human cornea to investigate possible mechanisms of adenoviral entry to specific corneal cell types.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0950-222X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12 ( Pt 2)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
273-7
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:9683953-Adenovirus Infections, Human,
pubmed-meshheading:9683953-Adenoviruses, Human,
pubmed-meshheading:9683953-Antigens, CD,
pubmed-meshheading:9683953-Cornea,
pubmed-meshheading:9683953-Endothelium, Corneal,
pubmed-meshheading:9683953-Epithelium, Corneal,
pubmed-meshheading:9683953-Eye Infections, Viral,
pubmed-meshheading:9683953-Gene Therapy,
pubmed-meshheading:9683953-Genetic Vectors,
pubmed-meshheading:9683953-Humans,
pubmed-meshheading:9683953-Immunoenzyme Techniques,
pubmed-meshheading:9683953-Integrin alphaV,
pubmed-meshheading:9683953-Integrins,
pubmed-meshheading:9683953-Keratoconjunctivitis,
pubmed-meshheading:9683953-Receptors, Vitronectin
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pubmed:year |
1998
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pubmed:articleTitle |
Distribution of integrins alpha v beta 5, alpha v beta 3 and alpha v in normal human cornea: possible implications in clinical and therapeutic adenoviral infection.
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pubmed:affiliation |
Department of Immunology, Imperial College School of Medicine, Hammersmith Hospital, London, UK. strayner@ic.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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