pubmed-article:9682356 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:9682356 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
pubmed-article:9682356 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
pubmed-article:9682356 | lifeskim:mentions | umls-concept:C0042200 | lld:lifeskim |
pubmed-article:9682356 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:9682356 | pubmed:issue | 9-10 | lld:pubmed |
pubmed-article:9682356 | pubmed:dateCreated | 1998-10-9 | lld:pubmed |
pubmed-article:9682356 | pubmed:abstractText | Annual influenza vaccine is recommended for persons with HIV infection. Recent reports indicate that immunizations may increase HIV replication in infected individuals. Forty-seven HIV-infected patients were randomized to influenza vaccine or saline placebo using a double blind study design. One month after vaccination, plasma HIV-1 RNA increased in the vaccinated but not placebo group (p = 0.029). At 3 months, CD4% dropped an average of 1.6 points in the vaccinated group compared to an increase of 0.1 points in the placebo group (p = 0.039). Patients on stable antiretroviral regimens had CD4% drop an average of 2.3 points in the vaccinated group at 3 months versus 0.1 points in the placebo group (p = 0.015). It is concluded that HIV-infected patients are at risk for increased HIV replication and decreases in CD4% following influenza vaccination. Since influenza has not been associated with significant morbidity in this population, further study of routine influenza vaccination for HIV-infected patients is warranted. | lld:pubmed |
pubmed-article:9682356 | pubmed:language | eng | lld:pubmed |
pubmed-article:9682356 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9682356 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:9682356 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9682356 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9682356 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:9682356 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:9682356 | pubmed:issn | 0264-410X | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:WallaceM RMR | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:WeissP JPJ | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:OlsonP EPE | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:TreanorJ JJJ | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:O'BrienW AWA | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:KaplanA HAH | lld:pubmed |
pubmed-article:9682356 | pubmed:author | pubmed-author:TassinM GMG | lld:pubmed |
pubmed-article:9682356 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:9682356 | pubmed:volume | 16 | lld:pubmed |
pubmed-article:9682356 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:9682356 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:9682356 | pubmed:pagination | 1039-42 | lld:pubmed |
pubmed-article:9682356 | pubmed:dateRevised | 2005-11-22 | lld:pubmed |
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pubmed-article:9682356 | pubmed:articleTitle | Effects of influenza vaccination in HIV-infected adults: a double-blind, placebo-controlled trial. | lld:pubmed |
pubmed-article:9682356 | pubmed:affiliation | Department of Internal Medicine (Infectious Diseases Division), Naval Medical Centre, San Diego, CA 92134-5000, USA. | lld:pubmed |
pubmed-article:9682356 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:9682356 | pubmed:publicationType | Clinical Trial | lld:pubmed |
pubmed-article:9682356 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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