| pubmed-article:9671455 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9671455 | lifeskim:mentions | umls-concept:C0035679 | lld:lifeskim |
| pubmed-article:9671455 | lifeskim:mentions | umls-concept:C0205160 | lld:lifeskim |
| pubmed-article:9671455 | lifeskim:mentions | umls-concept:C1446409 | lld:lifeskim |
| pubmed-article:9671455 | lifeskim:mentions | umls-concept:C1158830 | lld:lifeskim |
| pubmed-article:9671455 | lifeskim:mentions | umls-concept:C0182953 | lld:lifeskim |
| pubmed-article:9671455 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:9671455 | pubmed:dateCreated | 1998-8-21 | lld:pubmed |
| pubmed-article:9671455 | pubmed:abstractText | Activation of protein-encoding genes involves recruitment of an RNA polymerase II holoenzyme to promoters. Since the Srb4 subunit of the holoenzyme is essential for expression of most class II genes and is a target of at least one transcriptional activator, we reasoned that suppressors of a temperature-sensitive mutation in Srb4 would identify other factors generally involved in regulation of gene expression. We report here that MED6 and SRB6, both of which encode essential components of the holoenzyme, are among the dominant suppressors and that the products of these genes interact physically with Srb4. The recessive suppressors include NCB1 (BUR6), NCB2, NOT1, NOT3, NOT5, and CAF1, which encode subunits of NC2 and the Not complex. NC2 and Not proteins are general negative regulators which interact with TATA box binding protein (TBP). Taken together, these results suggest that transcription initiation involves a dynamic balance between activation mediated by specific components of the holoenzyme and repression by multiple TBP-associated regulators. | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9671455 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9671455 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9671455 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9671455 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:9671455 | pubmed:author | pubmed-author:YoungR ARA | lld:pubmed |
| pubmed-article:9671455 | pubmed:author | pubmed-author:LeeT ITI | lld:pubmed |
| pubmed-article:9671455 | pubmed:author | pubmed-author:GadboisE LEL | lld:pubmed |
| pubmed-article:9671455 | pubmed:author | pubmed-author:KohS SSS | lld:pubmed |
| pubmed-article:9671455 | pubmed:author | pubmed-author:WyrickJ JJJ | lld:pubmed |
