Linked Life Data

9671012

Source:http://linkedlifedata.com/resource/pubmed/id/9671012

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-8-5
pubmed:abstractText
Childhood supraventricular tachycardia (SVT) carries a good prognosis. Thus, treatment should be based on the use of drugs with a low risk of such potentially serious side effects as proarrhythmia, which is well documented for class I and III drugs in children. We studied all pediatric patients with a first manifestation of SVT between 1988 and the end of 1995 who were seen for a follow-up examination, including Holter monitoring, during 1996. The minimum follow-up period was 12 months. Fifty children met study entry criteria. Mean patient age at first presentation was 2 years (median 1 month), with 33 of the patients (66%) having experienced their first episode of tachycardia in their first year of life. Of 39 patients initially treated with either digoxin or a beta blocker, SVT in 29 (75%) responded favorably to this treatment. There were no adverse effects. Of the 10 children whose disease did not respond to these first-line agents, 9 (23% of those treated) required class I or III antiarrhythmic drugs. Thus, first-line antiarrhythmic long-term prophylaxis using drugs with a favorable risk profile, such as digoxin and beta blockers, resulted in successful disease management in a large proportion of unselected children, avoiding the need for chronic use of class I or class III antiarrhythmic drugs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
72-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Results of a restrictive use of antiarrhythmic drugs in the chronic treatment of atrioventricular reentrant tachycardias in infancy and childhood.
pubmed:affiliation
Division of Pediatric Cardiology, University Children's Hospital, Berne, Switzerland.
pubmed:publicationType
Journal Article