Linked Life Data

9667833

Source:http://linkedlifedata.com/resource/pubmed/id/9667833

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-9-15
pubmed:abstractText
To avoid the heterogeneous reaction conditions of solid-phase chemistry, liquid-phase synthesis provides homogeneity through the use of soluble polymer supports that can be selectively precipitated and filtered to achieve product purification. Peptides, oligonucleotides, and oligosaccharides have been synthesized by this method. Furthermore, combinatorial libraries of small molecules have been produced by liquid-phase synthesis to aid in the search for new pharmaceutical agents including compounds active against HIV. Soluble polymeric reagents have also been developed for greater ease and efficiency in organic synthesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1367-5931
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-13
pubmed:dateRevised
2009-8-25
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Synthesis on soluble polymers: new reactions and the construction of small molecules.
pubmed:affiliation
The Scripps Research Institute, Department of Chemistry, The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't