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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1998-11-30
|
| pubmed:abstractText |
Between January 1989 and June 1997, 533 patients (423 male, 110 female, mean age 61 years, range 22-89 years) with hepatocellular carcinoma (HCC) were observed at our center. We report on 419 patients retrospectively compared for different treatments: liver transplantation (LT; 55 patients), resective surgery (RS; 41 patients), transarterial chemoembolization (TACE; 171 patients) and percutaneous ethanol injection (PEI; 152 patients). The 3- and 5-year actuarial survival rates were, respectively, 72% and 68% for LT, 64 and 44% for RS, 54 and 36% for PEI, and 32 and 22% for TACE. Survival curves were compared for sex, age, tumor characteristics, alphafetoprotein level, Child class, and etiology of cirrhosis. All patient-related characteristics examined (sex, age) are not significantly related to patient survival. Tumor-related variables and associated liver disease variables significantly conditioned survival in relation to different treatments. LT seems to be the treatment of choice for monofocal HCC less then 5 cm in diameter and in selected cases of plurifocal HCC.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0934-0874
|
| pubmed:author |
pubmed-author:AlbertiAA,
pubmed-author:AseniPP,
pubmed-author:BelliL SLS,
pubmed-author:BottelliRR,
pubmed-author:ColellaGG,
pubmed-author:CortiAA,
pubmed-author:De CarlisLL,
pubmed-author:De GasperiAA,
pubmed-author:Di BenedettoFF,
pubmed-author:FinziMM,
pubmed-author:FolliniM LML,
pubmed-author:FortiDD,
pubmed-author:GelosaFF,
pubmed-author:IamoniG MGM,
pubmed-author:IdeoGG,
pubmed-author:ManochehriFF,
pubmed-author:MazzaEE,
pubmed-author:MeroniAA,
pubmed-author:RampoldiAA,
pubmed-author:RondinaraG FGF,
pubmed-author:SansaloneC VCV,
pubmed-author:SlimA OAO
|
| pubmed:issnType |
Print
|
| pubmed:volume |
11 Suppl 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
S193-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9664977-Actuarial Analysis,
pubmed-meshheading:9664977-Adult,
pubmed-meshheading:9664977-Aged,
pubmed-meshheading:9664977-Aged, 80 and over,
pubmed-meshheading:9664977-Carcinoma, Hepatocellular,
pubmed-meshheading:9664977-Chemoembolization, Therapeutic,
pubmed-meshheading:9664977-Ethanol,
pubmed-meshheading:9664977-Female,
pubmed-meshheading:9664977-Hepatectomy,
pubmed-meshheading:9664977-Humans,
pubmed-meshheading:9664977-Injections,
pubmed-meshheading:9664977-Liver Neoplasms,
pubmed-meshheading:9664977-Liver Transplantation,
pubmed-meshheading:9664977-Male,
pubmed-meshheading:9664977-Middle Aged,
pubmed-meshheading:9664977-Retrospective Studies,
pubmed-meshheading:9664977-Survival Rate
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Hepatocellular carcinoma: comparison between liver transplantation, resective surgery, ethanol injection, and chemoembolization.
|
| pubmed:affiliation |
Department of Surgery and Abdominal Organ Transplantation, Niguarda Hospital, Milan, Italy.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|