Linked Life Data

9664752

Source:http://linkedlifedata.com/resource/pubmed/id/9664752

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-8-25
pubmed:abstractText
Thirty-two patients suffering from migraine without aura were assessed during in interictal period to evaluate the contribution of cytokines to the pathophysiology of migraine. To this end, plasma levels of IFN-gamma, IL-4, IL-5, and IL-10 were measured by enzyme-linked immunosorbent assay (ELISA) techniques. Plasma levels of both IFN-gamma and IL-10 were not increased in the patients and did not differ significantly from healthy controls. Of interest, we observed a strong increase of IL-5 levels in 84.3% as well as increased IL-4 levels in 37.5% of patients with migraine without aura. These results suggests a preferential enhancement of some Th2-type cytokines, and may support the growing arguments of an immunoallergic mechanism in the pathophysiology of migraine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0017-8748
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
465-7
pubmed:dateRevised
2009-2-2
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Cytokines and migraine: increase of IL-5 and IL-4 plasma levels.
pubmed:affiliation
Dipartimento di Clinica Medica, Immunologia e Malattie Infettive -MIDIM-, Universitá di Bari, Italy.
pubmed:publicationType
Journal Article