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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1998-7-22
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pubmed:abstractText |
The class II human leukocyte Fcy receptor for IgG (FcgammaRIIa) occurs in 2 codominantly expressed allelic forms (R131 and H131). Cells expressing IIa-H131 interact much more effectively with complexed IgG2 and IgG3 than do cells with IIa-R131. This might be linked to variability in immune complex handling, and therefore related to disease pathogenesis. The present study examines these possibilities in a cohort of Caucasian patients with systemic lupus erythematosus (SLE).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:GeigerAA,
pubmed-author:KaldenJ RJR,
pubmed-author:MangelEE,
pubmed-author:MangerBB,
pubmed-author:RascuAA,
pubmed-author:ReppRR,
pubmed-author:SpriewaldB MBM,
pubmed-author:WassmuthRR,
pubmed-author:WentzBB,
pubmed-author:WesterdaalN ANA,
pubmed-author:van de WinkelJ GJG
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1181-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9663473-Adolescent,
pubmed-meshheading:9663473-Adult,
pubmed-meshheading:9663473-Age of Onset,
pubmed-meshheading:9663473-Aged,
pubmed-meshheading:9663473-Alleles,
pubmed-meshheading:9663473-Antigens, CD,
pubmed-meshheading:9663473-Child,
pubmed-meshheading:9663473-European Continental Ancestry Group,
pubmed-meshheading:9663473-Female,
pubmed-meshheading:9663473-HLA-DR Antigens,
pubmed-meshheading:9663473-Hematologic Diseases,
pubmed-meshheading:9663473-Humans,
pubmed-meshheading:9663473-Immune System Diseases,
pubmed-meshheading:9663473-Lupus Erythematosus, Systemic,
pubmed-meshheading:9663473-Male,
pubmed-meshheading:9663473-Middle Aged,
pubmed-meshheading:9663473-Polymorphism, Genetic,
pubmed-meshheading:9663473-Receptors, IgG
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pubmed:year |
1998
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pubmed:articleTitle |
Fcgamma receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: association with clinical symptoms.
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pubmed:affiliation |
University of Erlangen-Nuremberg, Erlangen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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