|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1998-8-18
|
|
pubmed:abstractText |
Aminoglycoside antibiotics bind to the A-site of the decoding region of 16S RNA in the bacterial ribosome, an interaction that is probably responsible for their activity. A detailed study of the specificity of aminoglycoside binding to A-site RNA would improve our understanding of their mechanism of antibiotic activity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1074-5521
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
397-406
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:9662506-Anti-Bacterial Agents,
pubmed-meshheading:9662506-Hydrogen-Ion Concentration,
pubmed-meshheading:9662506-Kanamycin,
pubmed-meshheading:9662506-Methylation,
pubmed-meshheading:9662506-Neomycin,
pubmed-meshheading:9662506-Osmolar Concentration,
pubmed-meshheading:9662506-Paromomycin,
pubmed-meshheading:9662506-RNA, Bacterial,
pubmed-meshheading:9662506-RNA, Ribosomal, 16S
|
|
pubmed:year |
1998
|
|
pubmed:articleTitle |
Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA.
|
|
pubmed:affiliation |
Department of Chemistry and the Skaggs Institute of Chemical Biology The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla, CA 92037, USA wong@scripps.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
