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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1976-11-21
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pubmed:abstractText |
Intraluminal perfusion of human jejunum has not been previously reported to demonstrate differences in bioavailability of vitamins from a food product. In this report, a triple lumen tube with a 30 cm study segment was used to study water soluble vitamin absorption in 15 normal subjects serving as their own controls. The intestinal uptake of vitamin B-6 from organ juice (O) and from a synthetic solution (S) perfused at 7.6 ml/minute were compared. In a separate series of perfusions in six subjects, the absorption of a mixture pf pyridoxine, pyridoxal, and pyridoxamine from O and S solutions with and without glucose were compared. Mean vitamin B-6 absorption was significantly greater from S (65% uptake, transport rate 0.71 mug/cm/hour) than from 9 (30% uptake, transport rate 0.40 mug/cm/hour, p less than 0.05). The addition of glucose to S enhanced this difference. Triple lumen intestinal perfusion can be used to discriminate difference in bioavailability of water soluble vitamins from natural and synthetic sources.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-3166
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
106
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1433-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:966070-Biological Availability,
pubmed-meshheading:966070-Citrus,
pubmed-meshheading:966070-Humans,
pubmed-meshheading:966070-Intestinal Absorption,
pubmed-meshheading:966070-Jejunum,
pubmed-meshheading:966070-Perfusion,
pubmed-meshheading:966070-Pyridoxal,
pubmed-meshheading:966070-Pyridoxamine,
pubmed-meshheading:966070-Pyridoxine
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pubmed:year |
1976
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pubmed:articleTitle |
Comparative human intestinal bioavailability of vitamin B-6 from a synthetic and a natural source.
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pubmed:publicationType |
Journal Article
|