Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-10-6
pubmed:abstractText
A new method was developed to measure total and regional cerebellar volumes using MRI. Previously, the volumes of the cerebellum and its substructure had been studied planimetrically. The new method uses three-dimensional semiautomated volumetry with focus on reliability and performance. The method consists of a manual presegmentation using landmark-adjusted planes followed by region-growing segmentation and calculation of volume. The cerebellum is partitioned into 11 regions defined by planes, which are adjusted for internal cerebellar landmarks (three radial regions inside the vermis that extend into the medial hemisphere (one-fourth of the transverse diameter of the hemisphere); one region in the lateral hemisphere (remaining three-fourths)). Forty-six healthy volunteers were examined and the effects of age, gender, and symmetry were estimated. Shrinkage in the vermis (especially anterior superior compartment) was marked. Age effects diminished laterally and were not observed in the lateral hemisphere. Age effects on the total cerebellar volume were marginal. Effects of gender and symmetry were nonsignificant. Technique and results are discussed and related to methods and findings of others.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0740-3194
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
143-51
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
A new semiautomated, three-dimensional technique allowing precise quantification of total and regional cerebellar volume using MRI.
pubmed:affiliation
Department of Neuroradiology, University of Tübingen, Germany.
pubmed:publicationType
Journal Article, Clinical Trial