Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1998-7-14
pubmed:abstractText
To examine the apoptotic effect induced in human retinoblastoma Y79 cells by camptothecin, etoposide, and amsacrine, to examine the effect of these drugs on the expression of many apoptosis-related modulators, and to test the antiapoptotic effect exerted by insulin-like growth factor-I (IGF-I).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Amsacrine, http://linkedlifedata.com/resource/pubmed/chemical/BAX protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CDKN1A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/Cyclins, http://linkedlifedata.com/resource/pubmed/chemical/Cycloheximide, http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm, http://linkedlifedata.com/resource/pubmed/chemical/DNA Topoisomerases, Type I, http://linkedlifedata.com/resource/pubmed/chemical/Dactinomycin, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Etoposide, http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor Binding..., http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2, http://linkedlifedata.com/resource/pubmed/chemical/Topoisomerase I Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53, http://linkedlifedata.com/resource/pubmed/chemical/bcl-2-Associated X Protein
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1300-11
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:9660477-Amsacrine, pubmed-meshheading:9660477-Apoptosis, pubmed-meshheading:9660477-Camptothecin, pubmed-meshheading:9660477-Cell Survival, pubmed-meshheading:9660477-Cyclin-Dependent Kinase Inhibitor p21, pubmed-meshheading:9660477-Cyclins, pubmed-meshheading:9660477-Cycloheximide, pubmed-meshheading:9660477-DNA, Neoplasm, pubmed-meshheading:9660477-DNA Damage, pubmed-meshheading:9660477-DNA Topoisomerases, Type I, pubmed-meshheading:9660477-Dactinomycin, pubmed-meshheading:9660477-Enzyme Inhibitors, pubmed-meshheading:9660477-Etoposide, pubmed-meshheading:9660477-Humans, pubmed-meshheading:9660477-Insulin-Like Growth Factor Binding Protein 3, pubmed-meshheading:9660477-Proto-Oncogene Proteins, pubmed-meshheading:9660477-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:9660477-Retinal Neoplasms, pubmed-meshheading:9660477-Retinoblastoma, pubmed-meshheading:9660477-Topoisomerase I Inhibitors, pubmed-meshheading:9660477-Tumor Cells, Cultured, pubmed-meshheading:9660477-Tumor Suppressor Protein p53, pubmed-meshheading:9660477-bcl-2-Associated X Protein
pubmed:year
1998
pubmed:articleTitle
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors.
pubmed:affiliation
Institute of Biological Chemistry, University of Palermo, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't