Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-7-16
pubmed:abstractText
The aim of the present investigation was to study the frequency of Shigella spp. in patients with bloody diarrhea in Pakistan and the susceptibility of isolated Shigella to three antibiotics: ampicillin, cotrimoxazole and nalidixic acid. In addition, the frequency of Campylobacter and Salmonella was also determined. Stool samples (n = 152) were collected from 152 diarrheic children less than six years of age passing blood and mucus in their stools who were admitted to Paediatric Department of Mayo Hospital in Lahore, Pakistan from June to September 1990. The samples were cultivated on standard media for Shigella, Campylobacter, and Salmonella. Susceptibility of Shigella isolates was tested by disk diffusion method. The frequency of isolation was 19.1% for Shigella spp., 7.9% for Campylobacter, and 4.6% for Salmonella. Shigella flexneri (7.9%) was the most frequently isolated species, followed by S. dysenteriae (6.6%), S. boydii, (3.3%) and S. sonnei (1.3%). All Shigella isolates were susceptible to nalidixic acid (100%), while only a few were susceptible to cotrimoxazole (7.0%) and ampicillin (3.5%). In Pakistan, self-medication and purchases of drugs without a prescription are commonly practiced. Thus, there is a greater possibility of development of resistant strains due to over use of antibiotics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9637
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
800-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9660467-Age Factors, pubmed-meshheading:9660467-Ampicillin, pubmed-meshheading:9660467-Anti-Bacterial Agents, pubmed-meshheading:9660467-Campylobacter, pubmed-meshheading:9660467-Child, Preschool, pubmed-meshheading:9660467-Diarrhea, pubmed-meshheading:9660467-Dysentery, Bacillary, pubmed-meshheading:9660467-Feces, pubmed-meshheading:9660467-Female, pubmed-meshheading:9660467-Gastrointestinal Hemorrhage, pubmed-meshheading:9660467-Humans, pubmed-meshheading:9660467-Incidence, pubmed-meshheading:9660467-Infant, pubmed-meshheading:9660467-Infant, Newborn, pubmed-meshheading:9660467-Male, pubmed-meshheading:9660467-Nalidixic Acid, pubmed-meshheading:9660467-Pakistan, pubmed-meshheading:9660467-Penicillins, pubmed-meshheading:9660467-Salmonella, pubmed-meshheading:9660467-Shigella, pubmed-meshheading:9660467-Trimethoprim-Sulfamethoxazole Combination
pubmed:year
1998
pubmed:articleTitle
Occurrence and susceptibility to antibiotics of Shigella species in stools of hospitalized children with bloody diarrhea in Pakistan.
pubmed:affiliation
Department of Paediatrics, King Edward Medical College, Lahore, Pakistan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't