Linked Life Data

9659610

Source:http://linkedlifedata.com/resource/pubmed/id/9659610

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-9-28
pubmed:abstractText
Basic fibroblast growth factor (bFGF) is well known as a potent angiogenic factor playing a crucial role in wound-healing processes. Apatitic substrates such as hydroxyapatite and carbonated apatite (CA) could be potential carriers of growth factors because of their physicochemical similarities to bone mineral. These materials have been compared for their bFGF adsorption and release properties. The adsorption of the growth factor was higher on carbonated apatite than on hydroxyapatite, probably owing to environments with labile nonapatitic CO3(2-) and HPO4(2-) groups, along with a higher specific surface area which gives the CA a higher surface reactivity. These environments can be exchanged very rapidly, leading to the release of bFGF. The controlled release of adsorbed growth factor from carbonated apatite could provide means of improving bone healing in the future.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0021-9304
pubmed:author
pubmed:issnType
Print
pubmed:day
5
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Basic fibroblast growth factor adsorption and release properties of calcium phosphate.
pubmed:affiliation
Laboratoire des Matériaux, Physico-chimie des Phosphates, UPRESA CNRS 5071, Toulouse, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't