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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1998-9-17
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pubmed:abstractText |
The Type I interferons are a family of closely related cytokines that have antiviral and immunostimulatory properties. There has been prolonged debate regarding the different interferon-alpha subtypes: with some authorities suggest that the different interferons have essentially similar properties but others argue that there are significant differences between them. Recent work has shown that the various interferon-alpha subtypes can interact with the interferon receptor components in different ways and can activate a number of different signalling pathways. Recent studies on the immunomodulatory properties of the Type I interferons indicate that there are profound differences between the subtypes. The clinical significance of all these differences remains to be determined.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-beta,
http://linkedlifedata.com/resource/pubmed/chemical/interferon omega 1
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1352-0504
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
143-52
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:9658366-Animals,
pubmed-meshheading:9658366-Antibodies,
pubmed-meshheading:9658366-Humans,
pubmed-meshheading:9658366-Interferon Type I,
pubmed-meshheading:9658366-Interferon-alpha,
pubmed-meshheading:9658366-Interferon-beta,
pubmed-meshheading:9658366-Signal Transduction,
pubmed-meshheading:9658366-Virus Diseases
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pubmed:year |
1998
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pubmed:articleTitle |
Are all type I human interferons equivalent?
|
pubmed:affiliation |
Imperial College School of Medicine, St Mary's Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Review
|