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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1998-7-31
|
| pubmed:abstractText |
Idiopathic retroperitoneal fibrosis (IRF) is a rare urological disease, for which many pathogenic theories have been proposed. The authors report a series of 13 cases of IRF in order to evaluate the clinical, diagnostic, laboratory, therapeutic and prognostic aspects. They also report a rare case (the ninth case reported in the literature) of multifocal fibrosclerosis. A possible genetic predisposition was studied by testing for the presence of immunophenotype HLA-B27; this test was positive in 44% of cases. A study of the immunological profile and lymphocyte populations revealed the typical features of chronic immune disease. Experience with medical and surgical treatment is reported, comparing various procedures: ureterolysis followed by application of a vascularized omental flap over the ureter (without subsequent corticosteroid therapy) gave the best results, with complete resolution of the symptoms and long-term successful alleviation of ureteric obstruction in 100% of patients, with a mean follow-up of 58 months.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0003-4401
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
32
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
153-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9657032-Adult,
pubmed-meshheading:9657032-Aged,
pubmed-meshheading:9657032-Anti-Inflammatory Agents,
pubmed-meshheading:9657032-Chronic Disease,
pubmed-meshheading:9657032-Female,
pubmed-meshheading:9657032-Follow-Up Studies,
pubmed-meshheading:9657032-Genetic Predisposition to Disease,
pubmed-meshheading:9657032-HLA-B27 Antigen,
pubmed-meshheading:9657032-Humans,
pubmed-meshheading:9657032-Immunophenotyping,
pubmed-meshheading:9657032-Longitudinal Studies,
pubmed-meshheading:9657032-Lymphocyte Subsets,
pubmed-meshheading:9657032-Male,
pubmed-meshheading:9657032-Middle Aged,
pubmed-meshheading:9657032-Omentum,
pubmed-meshheading:9657032-Prednisolone,
pubmed-meshheading:9657032-Prognosis,
pubmed-meshheading:9657032-Retroperitoneal Fibrosis,
pubmed-meshheading:9657032-Sclerosis,
pubmed-meshheading:9657032-Ureter,
pubmed-meshheading:9657032-Ureteral Obstruction
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Aetiopathogenesis and treatment of idiopathic retroperitoneal fibrosis.
|
| pubmed:affiliation |
Department of Surgical and Medical Disciplines, University Scholl of Medicine, Torino, Italy.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|