Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1978-8-14
pubmed:abstractText
The success of p-aminosalicyclic acid (PAS) and 1,2-cyclohexylene dinitrilotetraacetic acid (CDTA) in the mobilization of manganese from some vital organs and their subcellular fractions of manganese-intoxicated rats, led to the two compounds beng further investigated individually and in combination for their efficacy in influencing excretion of manganese in rabbits given MnO2. These chelating agents led to a higher excretion of manganese through faeces than urine. Whereas CDTA was able to enhance the excretion of manganese significantly through both routes, PAS could do so through faeces only. However, the combination did not improve upon the effect of the individual compounds.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0300-483X
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
379-85
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Chelation in metal intoxication. VI. Influence of PAS and CDTA on the excretion of manganese in rabbits given MnO2.
pubmed:publicationType
Journal Article, Comparative Study