Linked Life Data

9653773

Source:http://linkedlifedata.com/resource/pubmed/id/9653773

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1998-10-15
pubmed:abstractText
Both Day 14 corpora lutea (CL) of the estrous cycle and Day 200 CL of pregnancy secrete detectable prostaglandin E (PGE) and prostaglandin F2 alpha (PGF2 alpha) in vitro. Corpora lutea from Day 200 pregnant cows secrete more PGE and PGF alpha in vitro than Day 14 CL of the estrous cycle when incubated in control medium without treatments (p < or = 0.05). In addition, secretion of both PGE and PGF2 alpha in vitro by both Day 200 CL of pregnancy and Day 14 of the estrous cycle increase (p < or = 0.05) with time in culture in the absence of treatments. The PGE:PGF2 alpha ratio secreted at 4 h in the absence of treatments by Day 14 CL of the estrous cycle was 1.2 and at 8 h was 1.0 and did not differ (p > or = 0.05), while the PGE:PGF2 alpha ratio secreted by 200 day CL of pregnancy in the absence of treatments at 4 h was 0.8 and at 8 h decreased (p < or = 0.05) to 0.4. The PGE:PGF2 alpha ratio at 8 h by 200 day CL of pregnancy was lower (p < or = 0.05) than in the Day 14 CL of the estrous cycle at 4 or 8 h. Secretion of PGE or PGF2 alpha was affected by luteinizing hormone, PGE2, 8-Epi-PGE1, 8-Epi-PGE2, trichosanthin, and pregnancy specific protein B (PSPB) and was time and dose dependent (p < or = 0.05). In summary, the altered ratio of PGE:PGF2 alpha may explain the decreased secretion of progesterone at 8 h by Day 200 CL of pregnancy reported previously from the same samples. In addition, caution should be exercised in interpretation of progesterone secretion data with bovine CL studies in vitro. Also, PSPB may play an indirect role through PGE to regulate bovine luteal secretion of progesterone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1098-8823
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-76
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Effects of luteinizing hormone (LH), PGE2, 8-Epi-PGE1, 8-Epi-PGF2 alpha, trichosanthin and pregnancy specific protein B (PSPB) on secretion of prostaglandin (PG) E (PGE) or F2 alpha (PGF2 alpha) in vitro by corpora lutea (CL) from nonpregnant and pregnant cows.
pubmed:affiliation
Department of Animal Sciences, University of Hawaii, Honolulu 96822, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't