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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-8-10
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pubmed:abstractText |
Birth asphyxia represents a serious problem worldwide, resulting in approximately 1 million deaths and an equal number of serious sequelae annually. It is therefore important to develop new and better ways to treat asphyxia. Resuscitation after birth asphyxia traditionally has been carried out with 100% oxygen, and most guidelines and textbooks recommend this; however, the scientific background for this has never been established. On the contrary, theoretic considerations indicate that resuscitation with high oxygen concentrations could have detrimental effects. We have performed a series of animal studies as well as one pilot study indicating that resuscitation can be performed with room air just as efficiently as with 100% oxygen. To test this more thoroughly, we organized a multicenter study and hypothesized that room air is superior to 100% oxygen when asphyxiated newborn infants are resuscitated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1098-4275
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e1
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9651453-Acid-Base Equilibrium,
pubmed-meshheading:9651453-Air,
pubmed-meshheading:9651453-Analysis of Variance,
pubmed-meshheading:9651453-Apgar Score,
pubmed-meshheading:9651453-Asphyxia Neonatorum,
pubmed-meshheading:9651453-Birth Weight,
pubmed-meshheading:9651453-Confidence Intervals,
pubmed-meshheading:9651453-Female,
pubmed-meshheading:9651453-Fetal Blood,
pubmed-meshheading:9651453-Gestational Age,
pubmed-meshheading:9651453-Heart Rate,
pubmed-meshheading:9651453-Humans,
pubmed-meshheading:9651453-Infant, Newborn,
pubmed-meshheading:9651453-Male,
pubmed-meshheading:9651453-Odds Ratio,
pubmed-meshheading:9651453-Oxygen,
pubmed-meshheading:9651453-Prospective Studies,
pubmed-meshheading:9651453-Resuscitation,
pubmed-meshheading:9651453-Survival Rate,
pubmed-meshheading:9651453-Treatment Failure,
pubmed-meshheading:9651453-Treatment Outcome
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pubmed:year |
1998
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pubmed:articleTitle |
Resuscitation of asphyxiated newborn infants with room air or oxygen: an international controlled trial: the Resair 2 study.
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pubmed:affiliation |
Department of Pediatric Research, National Hospital, Oslo, Norway.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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