Linked Life Data

9649941

Source:http://linkedlifedata.com/resource/pubmed/id/9649941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-9-28
pubmed:abstractText
Left-right asymmetric looping of the cardiac tube during embryogenesis places the segments of the cardiac tube that give rise to the left and right chambers into their appropriate spatial orientation. Cardiac looping is required for subsequent formation of septa, valves, and outflow tract. Defects in embryonic left-right axis formation represent a significant portion of congenital heart malformations. Recent discoveries make it apparent that the orientation of cardiac tube looping is dependent on a cascade of genes in noncardiac embryonic cells, including lateral cells and midline cells, before neural tube closure. These observations suggest a linkage between complex cardiac defects and subtle midline defects in early embryos.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0268-4705
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The genetics of midline and cardiac laterality defects.
pubmed:affiliation
Huntsman Cancer Institute Center for Children, Department of Oncological Sciences, University of Utah, Salt Lake City 84103, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't