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rdf:type |
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lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0019904,
umls-concept:C0031327,
umls-concept:C0052944,
umls-concept:C0205182,
umls-concept:C0681850,
umls-concept:C0728810,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
5
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pubmed:dateCreated |
1998-9-1
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pubmed:abstractText |
It has been assumed that both plasma cholinesterase (EC 3.1.1.8) and oxidative enzymes are needed for optimum formation of the bronchodilator terbutaline from its biscarbamate prodrug bambuterol. The present study aimed at investigating the fate of bambuterol in subjects with deficient plasma cholinesterase but with normal oxidative (CYP2D6) capability.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-13240528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-1747920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-1994894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-2244449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-2244450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-2340359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-3069421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-3168394,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-4042522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-6345094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-6992635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-7640151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-7793180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-8487254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9643621-9643620
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0306-5251
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
479-84
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:9643621-Adult,
pubmed-meshheading:9643621-Area Under Curve,
pubmed-meshheading:9643621-Bronchodilator Agents,
pubmed-meshheading:9643621-Cholinesterases,
pubmed-meshheading:9643621-Debrisoquin,
pubmed-meshheading:9643621-Female,
pubmed-meshheading:9643621-Genotype,
pubmed-meshheading:9643621-Half-Life,
pubmed-meshheading:9643621-Humans,
pubmed-meshheading:9643621-Male,
pubmed-meshheading:9643621-Metabolic Clearance Rate,
pubmed-meshheading:9643621-Middle Aged,
pubmed-meshheading:9643621-Prodrugs,
pubmed-meshheading:9643621-Sympatholytics,
pubmed-meshheading:9643621-Terbutaline
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pubmed:year |
1998
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pubmed:articleTitle |
Pharmacokinetics of bambuterol in subjects homozygous for the atypical gene for plasma cholinesterase.
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pubmed:affiliation |
Department of Anaesthesia, Skejby Sygehus, Aarhus N, Denmark.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
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