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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1998-7-23
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pubmed:abstractText |
Nodular localized cutaneous amyloidosis (NLCA) is a disorder characterized by deposition of amyloid derived from immunoglobulin light chains. We used semi-nested polymerase chain reaction (PCR) to analyse archival paraffin-embedded sections from a previous patient and from four additional, previously reported patients with NLCA to determine whether involvement of monoclonal plasma cells is a universal feature of this condition. The semi-nested PCR analysis revealed one or two amplified bands, around 100-120 bp, for all five cases of NLCA, although the yields varied from case to case. These results suggest that clonal expansion of plasma cells in NLCA may occur locally.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
652-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9640373-Adult,
pubmed-meshheading:9640373-Aged,
pubmed-meshheading:9640373-Amyloidosis,
pubmed-meshheading:9640373-Clone Cells,
pubmed-meshheading:9640373-Female,
pubmed-meshheading:9640373-Humans,
pubmed-meshheading:9640373-Male,
pubmed-meshheading:9640373-Middle Aged,
pubmed-meshheading:9640373-Paraffin Embedding,
pubmed-meshheading:9640373-Plasma Cells,
pubmed-meshheading:9640373-Polymerase Chain Reaction,
pubmed-meshheading:9640373-Skin Diseases
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pubmed:year |
1998
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pubmed:articleTitle |
Nodular localized cutaneous amyloidosis: further demonstration of monoclonality of infiltrating plasma cells in four additional Japanese patients.
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pubmed:affiliation |
Department of Dermatology, Faculty of Medicine, Tottori University, Yonago, Japan. yohagari@grape.med.tottori-u.ac.jp
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pubmed:publicationType |
Journal Article
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