rdf:type |
|
lifeskim:mentions |
umls-concept:C0003591,
umls-concept:C0020443,
umls-concept:C0023779,
umls-concept:C0030705,
umls-concept:C0074554,
umls-concept:C0082608,
umls-concept:C0151744,
umls-concept:C0205081,
umls-concept:C0229671,
umls-concept:C0301630,
umls-concept:C1707455
|
pubmed:issue |
1
|
pubmed:dateCreated |
1998-9-9
|
pubmed:abstractText |
Inhibitors of HMG-CoA reductase are widely used for the treatment of hypercholesterolaemia and have recently been shown in the Scandinavian Simvastatin Survival Study (4S), to reduce coronary mortality as well as total mortality in CH D patients. Although a couple of studies have already established the efficacy ratio between simvastatin and fluvastatin, one of the newest members of this class, we considered it to be important to verify the comparative efficacy in patients with coronary artery disease in the same type of patients that were included in 4S particularly since the previous studies include rather few patients with CHD, 17-28% only.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-5385
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
53
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
7-14
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:9638964-Analysis of Variance,
pubmed-meshheading:9638964-Apolipoproteins,
pubmed-meshheading:9638964-Double-Blind Method,
pubmed-meshheading:9638964-Fatty Acids, Monounsaturated,
pubmed-meshheading:9638964-Female,
pubmed-meshheading:9638964-Humans,
pubmed-meshheading:9638964-Hypercholesterolemia,
pubmed-meshheading:9638964-Hypolipidemic Agents,
pubmed-meshheading:9638964-Indoles,
pubmed-meshheading:9638964-Likelihood Functions,
pubmed-meshheading:9638964-Lipids,
pubmed-meshheading:9638964-Male,
pubmed-meshheading:9638964-Middle Aged,
pubmed-meshheading:9638964-Myocardial Ischemia,
pubmed-meshheading:9638964-Simvastatin,
pubmed-meshheading:9638964-Statistics, Nonparametric
|
pubmed:year |
1998
|
pubmed:articleTitle |
Simvastatin compared to fluvastatin in the reduction of serum lipids and apolipoproteins in patients with ischaemic heart disease and moderate hypercholesterolaemia.
|
pubmed:affiliation |
Sjúkrahús Reykjavíkur Fossvogi, Reykjavik, Iceland.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|