| pubmed-article:9634510 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9634510 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
| pubmed-article:9634510 | lifeskim:mentions | umls-concept:C0599883 | lld:lifeskim |
| pubmed-article:9634510 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:9634510 | lifeskim:mentions | umls-concept:C1283195 | lld:lifeskim |
| pubmed-article:9634510 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9634510 | pubmed:dateCreated | 1998-8-13 | lld:pubmed |
| pubmed-article:9634510 | pubmed:abstractText | Molecular geneticists are developing the third-generation human genome map with single-nucleotide polymorphisms (SNPs), which can be assayed via chip-based microarrays. One use of these SNP markers is the ability to locate loci that may be responsible for complex traits, via linkage/linkage-disequilibrium analysis. In this communication, we describe a semiparametric method for combined linkage/linkage-disequilibrium analysis using SNP markers. Asymptotic results are obtained for the estimated parameters, and the finite-sample properties are evaluated via a simulation study. We also applied this technique to a simulated genome-scan experiment for mapping a complex trait with two major genes. This experiment shows that separate linkage and linkage-disequilibrium analyses correctly detected the signals of both major genes; but the rates of false-positive signals seem high. When linkage and linkage-disequilibrium signals were combined, the analysis yielded much stronger and clearer signals for the presence of two major genes than did two separate analyses. | lld:pubmed |
| pubmed-article:9634510 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9634510 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9634510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9634510 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9634510 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:9634510 | pubmed:issn | 0002-9297 | lld:pubmed |
| pubmed-article:9634510 | pubmed:author | pubmed-author:IUSAA | lld:pubmed |
| pubmed-article:9634510 | pubmed:author | pubmed-author:ZhaoL PLP | lld:pubmed |
| pubmed-article:9634510 | pubmed:author | pubmed-author:QuiaoitFF | lld:pubmed |
| pubmed-article:9634510 | pubmed:author | pubmed-author:AragakiCC | lld:pubmed |
| pubmed-article:9634510 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9634510 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:9634510 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9634510 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9634510 | pubmed:pagination | 225-40 | lld:pubmed |
| pubmed-article:9634510 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:meshHeading | pubmed-meshheading:9634510-... | lld:pubmed |
| pubmed-article:9634510 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9634510 | pubmed:articleTitle | Mapping of complex traits by single-nucleotide polymorphisms. | lld:pubmed |
| pubmed-article:9634510 | pubmed:affiliation | Quantitative Genetic Epidemiology Group, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. lzhao@fhcrc.org | lld:pubmed |
| pubmed-article:9634510 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9634510 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9634510 | lld:pubmed |
