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pubmed:abstractText |
Radiotherapeutic efficacious of the compounds from major organs and tissues of Central Asian tortoise--the animal known for its unique radioresistance, has been checked up. Along with the so well-known compounds as the plasma ones, tortoise spleen extracts (TSE) and the ones from the liver of adult animals and embryos, extracts from kidneys and muscles have been shown to increase the survivability rate of irradiated rats and mice. The compound, that called "Tortezin" shows the highest blood cell cytosol effect. The specific activity and the output are 4 and 12 times higher, than the ones of TSE, respectively. Dose increase factor (DIF) reaches as far as 1.41. The compound possesses considerable immunostimulating activity. The detailed physico-chemical characteristics of the compound, quite sufficient for its identification has been made.
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