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rdf:type |
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|
lifeskim:mentions |
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|
pubmed:issue |
6 Pt 2
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|
pubmed:dateCreated |
1998-7-7
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|
pubmed:abstractText |
Fluconazole has proven to be safe and effective for a variety of superficial and systemic fungal infections. Preliminary analysis of extensive Phase III studies suggests that it is very effective for the treatment of onychomycosis. Its pharmacokinetic properties, including low molecular weight and high water-solubility, suggest a unique ability to penetrate the nail. This feature is likely to account in part for fluconazole's effectiveness in the treatment of onychomycosis.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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|
pubmed:issn |
0190-9622
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pubmed:author |
pubmed-author:BabelDD,
pubmed-author:BrenemanDD,
pubmed-author:BuckoA DAD,
pubmed-author:DrakeLL,
pubmed-author:ElewskiB EBE,
pubmed-author:EllisC NCN,
pubmed-author:FriedmanDD,
pubmed-author:HanifinJ MJM,
pubmed-author:HilbertJJ,
pubmed-author:KanoKK,
pubmed-author:LEVYJ GJG,
pubmed-author:LeydenJ JJJ,
pubmed-author:LinkM FMF,
pubmed-author:MartinA GAG,
pubmed-author:McDonaldC JCJ,
pubmed-author:MormanM RMR,
pubmed-author:MugliaJJ,
pubmed-author:PariserD MDM,
pubmed-author:PariserR JRJ,
pubmed-author:RichPP,
pubmed-author:SavinR CRC,
pubmed-author:ScherR KRK,
pubmed-author:StewartD MDM,
pubmed-author:TschenE HEH,
pubmed-author:WebsterGG
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pubmed:issnType |
Print
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|
pubmed:volume |
38
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
N
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pubmed:pagination |
S110-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9631993-Adult,
pubmed-meshheading:9631993-Aged,
pubmed-meshheading:9631993-Antifungal Agents,
pubmed-meshheading:9631993-Drug Administration Schedule,
pubmed-meshheading:9631993-Female,
pubmed-meshheading:9631993-Fluconazole,
pubmed-meshheading:9631993-Hand Dermatoses,
pubmed-meshheading:9631993-Humans,
pubmed-meshheading:9631993-Male,
pubmed-meshheading:9631993-Middle Aged,
pubmed-meshheading:9631993-Nails,
pubmed-meshheading:9631993-Onychomycosis,
pubmed-meshheading:9631993-Time Factors
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pubmed:year |
1998
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|
pubmed:articleTitle |
Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail.
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pubmed:affiliation |
Savin Dermatology Center, New Haven, Connecticut 06511, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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