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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1998-8-24
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pubmed:abstractText |
If gallamine or d-tubocurarine gains access to the central nervous system it produces a myoclonus, a synchronized jerking of many skeletal muscles. Each jerk is accompanied by a slow wave in the inferior olive. The jerking continues for 24 h or more after the gallamine or d-tubocurarine can no longer be detected in the CSF. We report here that a novel substance appears in the CSF and persists for a long period of time, possibly as long as the twitching. This substance is not corticotrophin-releasing factor (CRF) nor does CRF or harmaline (a substance causing a tremor by an action on the inferior olive) lead to the appearance of the novel substance. At present the nature of this substance is not known.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0959-4965
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1349-52
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:9631427-Animals,
pubmed-meshheading:9631427-Biological Factors,
pubmed-meshheading:9631427-Cats,
pubmed-meshheading:9631427-Chromatography, High Pressure Liquid,
pubmed-meshheading:9631427-Corticotropin-Releasing Hormone,
pubmed-meshheading:9631427-Decerebrate State,
pubmed-meshheading:9631427-Gallamine Triethiodide,
pubmed-meshheading:9631427-Myoclonus,
pubmed-meshheading:9631427-Olivary Nucleus,
pubmed-meshheading:9631427-Sensitivity and Specificity,
pubmed-meshheading:9631427-Time Factors,
pubmed-meshheading:9631427-Tubocurarine
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pubmed:year |
1998
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pubmed:articleTitle |
A novel substance associated with gallamine-induced myoclonus.
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pubmed:affiliation |
Department of Pharmacy, University of Sydney, NSW, Australia.
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pubmed:publicationType |
Journal Article
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