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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1998-7-1
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pubmed:abstractText |
To attempt to safely escalate the dose of radiation for patients with intrahepatic cancer, we designed a protocol in which each patient received the maximum possible dose while being subjected to a 10% risk of radiation-induced liver disease (RILD, or radiation hepatitis) based on a normal tissue complication probability (NTCP) model. We had two hypotheses: H1; with this approach, we could safely deliver higher doses of radiation than we would have prescribed based on our previous protocol, and H2; the model would predict the observed complication probability (10%).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0732-183X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2246-52
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9626227-Antimetabolites, Antineoplastic,
pubmed-meshheading:9626227-Combined Modality Therapy,
pubmed-meshheading:9626227-Floxuridine,
pubmed-meshheading:9626227-Humans,
pubmed-meshheading:9626227-Liver Neoplasms,
pubmed-meshheading:9626227-Models, Statistical,
pubmed-meshheading:9626227-Radiotherapy
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pubmed:year |
1998
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pubmed:articleTitle |
Treatment of intrahepatic cancers with radiation doses based on a normal tissue complication probability model.
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pubmed:affiliation |
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor 48109-0010, USA. mcginn@umich.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
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