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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
21
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pubmed:dateCreated |
1998-6-25
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pubmed:abstractText |
Coronary endothelial dysfunction is characterized by an imbalance between endothelium-derived vasodilating and vasoconstricting factors and coronary vasoconstriction in response to the endothelium-dependent vasodilator acetylcholine. Thus, the present double-blind, randomized study was designed to test the hypothesis that long-term, 6-month supplementation of L-arginine, the precursor of the endothelium-derived vasodilator NO, reverses coronary endothelial dysfunction to acetylcholine in humans with nonobstructive coronary artery disease.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0009-7322
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2123-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9626172-Adult,
pubmed-meshheading:9626172-Aged,
pubmed-meshheading:9626172-Arginine,
pubmed-meshheading:9626172-Coronary Vessels,
pubmed-meshheading:9626172-Double-Blind Method,
pubmed-meshheading:9626172-Endothelium, Vascular,
pubmed-meshheading:9626172-Female,
pubmed-meshheading:9626172-Humans,
pubmed-meshheading:9626172-Male,
pubmed-meshheading:9626172-Middle Aged,
pubmed-meshheading:9626172-Nitric Oxide
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pubmed:year |
1998
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pubmed:articleTitle |
Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans.
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pubmed:affiliation |
Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minn. 55905, USA. lerman.amir@mayo.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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