Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-10-20
pubmed:abstractText
The effect of acetylcholine on bile flow was studied in isolated perfused rat liver. Acetylcholine added into the perfusion medium altered bile flow in a way analogous to mechanical clamping and opening of the common bile duct. This effect was potentiated by physostigmine and antagonized by atropine. The results suggest that acetylcholine can pass from portal sinusoidal blood into the biliary tract, possibly through the terminal bars of bile canaliculi, and cause an obstruction in the biliary tree. Suggested mechanism could explain the observed decreased and increased bile flow caused by cholinergic drugs or vagal stimulation in the earlier experiments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0301-4533
pubmed:author
pubmed:issnType
Print
pubmed:volume
221
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
The effect of acetylcholine on bile flow.
pubmed:publicationType
Journal Article, In Vitro