|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1998-6-19
|
|
pubmed:abstractText |
A prospective comparison of metabolic and inflammatory responses after laparoscopic and open inguinal hernia operations was undertaken. There were 10 patients in each group. Plasma levels of cortisol, growth hormone, prolactin, C-reactive protein (CRP) and interleukin-6 (IL-6) were measured preoperatively and at fixed intervals up to 120 h postoperatively. In vitro, endotoxin stimulated whole blood tumour necrosis factor alpha (TNF alpha) was measured in preoperative and 24 h postoperative blood samples. Changes in the plasma levels of cortisol, growth hormone and prolactin showed no statistically significant difference between the groups. No significant change in IL-6 levels were recorded in any group. Changes in CRP levels were significantly higher (P < 0.006) in open hernia patients. Endotoxin stimulated TNF alpha production was suppressed in both groups. The degree of suppression in open hernia patients was significantly higher (P < 0.005). This study has shown that both these operations produce similar stress responses. However, open hernia operation results in a higher acute phase response and induces a greater endotoxin tolerance.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1292641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1393463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1431150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1444784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1455878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1932368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-1939659,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-2167805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-2200312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-2318968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-2589967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-2956717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-4634485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-6826776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-7482166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-7520075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-7826159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-8032001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-8242291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-8313088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9623379-8406740
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0035-8843
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
80
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
125-30
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:9623379-Acute-Phase Reaction,
pubmed-meshheading:9623379-Adult,
pubmed-meshheading:9623379-Aged,
pubmed-meshheading:9623379-C-Reactive Protein,
pubmed-meshheading:9623379-Endotoxins,
pubmed-meshheading:9623379-Female,
pubmed-meshheading:9623379-Growth Hormone,
pubmed-meshheading:9623379-Hernia, Inguinal,
pubmed-meshheading:9623379-Humans,
pubmed-meshheading:9623379-Hydrocortisone,
pubmed-meshheading:9623379-Laparoscopy,
pubmed-meshheading:9623379-Male,
pubmed-meshheading:9623379-Middle Aged,
pubmed-meshheading:9623379-Postoperative Complications,
pubmed-meshheading:9623379-Prolactin,
pubmed-meshheading:9623379-Prospective Studies,
pubmed-meshheading:9623379-Stress, Physiological,
pubmed-meshheading:9623379-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
1998
|
|
pubmed:articleTitle |
Metabolic and inflammatory responses after laparoscopic and open inguinal hernia repair.
|
|
pubmed:affiliation |
University Department of Surgery, Manchester Royal Infirmary.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial
|
