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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
1998-6-17
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pubmed:abstractText |
The alpha1-antichymotrypsin and apolipoprotein-E polymorphisms were investigated in patients suffering from Alzheimer's syndrome and non-demented psychiatric inpatients as controls. The apolipoprotein E allele 4, well known as risk factor, tended to be elevated in the index group. The frequency of the alpha1-antichymotrypsin allele A was significantly increased in patients with Alzheimer's syndrome: 0.647 vs. 0.483 (chi-square test, p < 0.05). We conclude that, apart from the apolipoprotein E allele 4, the alpha1-antichymotrypsin allele A possibly represents a second genetic factor increasing individual's risk for Alzheimer's syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0936-3076
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-12
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9620064-Aged,
pubmed-meshheading:9620064-Aged, 80 and over,
pubmed-meshheading:9620064-Alleles,
pubmed-meshheading:9620064-Alzheimer Disease,
pubmed-meshheading:9620064-Apolipoproteins E,
pubmed-meshheading:9620064-Female,
pubmed-meshheading:9620064-Genotype,
pubmed-meshheading:9620064-Humans,
pubmed-meshheading:9620064-Male,
pubmed-meshheading:9620064-Middle Aged,
pubmed-meshheading:9620064-Polymorphism, Genetic,
pubmed-meshheading:9620064-Risk Factors,
pubmed-meshheading:9620064-alpha 1-Antichymotrypsin
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pubmed:year |
1995
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pubmed:articleTitle |
Alpha-1-antichymotrypsin bi-allele polymorphism, apolipoprotein-E tri-allele polymorphism and genetic risk of Alzheimer's syndrome.
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pubmed:affiliation |
Department of Psychiatry, University of Würzburg, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article
|