Linked Life Data

9617492

Source:http://linkedlifedata.com/resource/pubmed/id/9617492

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1998-8-3
pubmed:abstractText
After having observed high serum ferritin concentrations in some patients with acute renal failure (ARF) we decided to evaluate serum ferritin and iron levels in patients with acute and chronic renal failure (CRF). The concentrations of BUN, serum creatinine, Hct, Hb, serum iron and serum ferritin were measured in 47 patients with renal failure who were divided into two groups (A and B). Group A included 24 patients with ARF (19 M, 5 F) and group B 23 patients with CRF (12 M, 11 F). The diagnosis of ARF or CRF was based on patients' history and clinical examination and confirmed by the standard laboratory findings and the subsequent clinical outcome. None of the patients had received iron, blood transfusions or erythropoietin during the last six months and none had malignancy or primary liver diseases. As controls were used 20 normal volunteers (group C) and 10 patients with acute infections (group D). Comparing groups A and B we did not found any difference in BUN, creatinine and serum iron levels. However patients in group A had significantly higher serum ferritin levels (1000 +/- 752 vs 90 +/- 56 ng/dl, p = 0.0001), higher Hct (31.8 +/- 4.4 vs 25.3 +/- 4.1%, p = 0.0001) and higher Hb concentrations (10.5 +/- 1.7 vs 8.1 +/- 1.4 g/dl, p = 0.0001). Ferritin levels in patients with ARF were also higher than the corresponding levels of normal controls (group C) (p = 0.0001), but did not differ significantly from those measured in patients with acute infection (group D). We conclude that in patients with acute renal failure serum ferritin levels are increased and do not reflect serum iron levels.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0301-0430
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
296-8
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Serum ferritin levels are increased in patients with acute renal failure.
pubmed:affiliation
Renal Unit, General Hospital G. Papanikolaou Thessaloniki, Greece.
pubmed:publicationType
Journal Article, Comparative Study