Linked Life Data

9612238

Source:http://linkedlifedata.com/resource/pubmed/id/9612238

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 1
pubmed:dateCreated
1998-7-1
pubmed:abstractText
Dual-energy X-ray absorptiometry (DXA) is rapidly gaining acceptance as a reference method for analyzing body composition. An important and unresolved concern is whether and to what extent variation in soft tissue hydration causes errors in DXA fat estimates. The present study aim was to develop and validate a DXA physical hydration model and then to apply this model by simulating errors arising from hypothetical overhydration states. The DXA physical hydration model was developed by first linking biological substance elemental content with photon attenuation. The validated physical model was next extended to describe photon attenuation changes anticipated when predefined amounts of two known composition components are mixed, as would occur when overhydration develops. Two overhydration models were developed in the last phase of study, formulated on validated physical models, and error was simulated for fluid surfeit states. Results indicate that systematic errors in DXA percent fat arise with added fluids when fractional masses are varied as a percentage of combined fluid + soft tissue mass. Three independent determinants of error magnitude were established: elemental content of overhydration fluid, fraction of combined fluid + soft tissue as overhydration fluid, and initial soft tissue composition. Small but systematic and predictable errors in DXA soft tissue composition analysis thus can arise with fluid balance changes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
274
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
E808-16
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Dual-energy X-ray absorptiometry: fat estimation errors due to variation in soft tissue hydration.
pubmed:affiliation
Obesity Research Center, St. Luke's-Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York 10025, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.