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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1998-9-10
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pubmed:abstractText |
Delta (Dl) and Hairless (H) are two chromosome 3 candidate neurogenic loci that might contribute to naturally occurring quantitative variation for sensory bristle number. To evaluate this hypothesis, we assessed quantitative genetic variation in abdominal and sternopleural bristle numbers among homozygous isogenic third chromosomes sampled from nature and substituted into the Samarkand (Sam) inbred chromosome 1 and 2 background; among homozygous lines in which the wild-derived Dl-H gene region was introgressed into the Sam chromosome 3 background; and among Dl-H region introgression lines as heterozygotes against the Sam wild-type strain and derivatives of Sam into which mutant Dl and H alleles had been introgressed. Variation among the Dl-H region introgression lines accounted for 36% (8.3%) of the total chromosome 3 among line variance in abdominal (sternopleural) bristle number and for 53% of the chromosome 3 sex x line variance in abdominal bristle number. Naturally occurring alleles in the Dl-H region failed to complement a Dl mutant allele for female abdominal bristle number and sternopleural bristle number in both sexes, and an H mutant allele for both bristle traits in males and females. These results are consistent with the hypothesis that naturally occurring alleles at Dl and H contribute to quantitative genetic variation in sensory bristle number.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-1311697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-1419850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-16593036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-17246416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-17246417,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-17246488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-1732160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-2694935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-2996979,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-3818341,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-415250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-4217752,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-5488984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-5713599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-5713600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-5960413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-7713436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-7716513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-7768438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-7992053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8005446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8122902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-814111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8234366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8346443,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8536981,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8722782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8807316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8844166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8889529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-8889533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-9275193,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-9383087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9611208-9611209
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0016-6731
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
149
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
983-98
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:9611208-Analysis of Variance,
pubmed-meshheading:9611208-Animals,
pubmed-meshheading:9611208-Chromosomes,
pubmed-meshheading:9611208-Drosophila Proteins,
pubmed-meshheading:9611208-Drosophila melanogaster,
pubmed-meshheading:9611208-Female,
pubmed-meshheading:9611208-Genes, Insect,
pubmed-meshheading:9611208-Genetic Complementation Test,
pubmed-meshheading:9611208-Genetic Variation,
pubmed-meshheading:9611208-Genotype,
pubmed-meshheading:9611208-Heterozygote,
pubmed-meshheading:9611208-Homozygote,
pubmed-meshheading:9611208-Insect Proteins,
pubmed-meshheading:9611208-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:9611208-Linear Models,
pubmed-meshheading:9611208-Male,
pubmed-meshheading:9611208-Membrane Proteins,
pubmed-meshheading:9611208-Phenotype,
pubmed-meshheading:9611208-Quantitative Trait, Heritable,
pubmed-meshheading:9611208-Statistical Distributions,
pubmed-meshheading:9611208-Transcription Factors
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pubmed:year |
1998
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pubmed:articleTitle |
Candidate quantitative trait loci and naturally occurring phenotypic variation for bristle number in Drosophila melanogaster: the Delta-Hairless gene region.
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pubmed:affiliation |
Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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