9609760

Source:http://linkedlifedata.com/resource/pubmed/id/9609760

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008059, umls-concept:C0013081, umls-concept:C0083183, umls-concept:C2728259
pubmed:issue	6
pubmed:dateCreated	1998-7-9
pubmed:abstractText	Intestinal lactase activity is high in all healthy human babies, but in adults a genetic polymorphism, which acts in cis to the lactase gene, determines high or low messenger RNA (mRNA) expression and activity (lactase persistence and nonpersistence, respectively). Our aim was to investigate the onset of expression of this polymorphism in children.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374630
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Lactase, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/beta-Galactosidase
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0016-5085
pubmed:author	pubmed-author:ClayPP, pubmed-author:HarveyC BCB, pubmed-author:HolloxE JEJ, pubmed-author:PhillipsA DAD, pubmed-author:PoulterMM, pubmed-author:SwallowD MDM, pubmed-author:Walker-SmithJ AJA, pubmed-author:WangYY
pubmed:issnType	Print
pubmed:volume	114
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1230-6
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:9609760-Adolescent, pubmed-meshheading:9609760-Adult, pubmed-meshheading:9609760-Alleles, pubmed-meshheading:9609760-Biopsy, pubmed-meshheading:9609760-Child, pubmed-meshheading:9609760-Child, Preschool, pubmed-meshheading:9609760-Child Development, pubmed-meshheading:9609760-Fetus, pubmed-meshheading:9609760-Gene Expression Regulation, pubmed-meshheading:9609760-Humans, pubmed-meshheading:9609760-Infant, pubmed-meshheading:9609760-Infant, Newborn, pubmed-meshheading:9609760-Intestines, pubmed-meshheading:9609760-Lactase, pubmed-meshheading:9609760-Polymorphism, Genetic, pubmed-meshheading:9609760-Prospective Studies, pubmed-meshheading:9609760-RNA, Messenger, pubmed-meshheading:9609760-Reference Values, pubmed-meshheading:9609760-Retrospective Studies, pubmed-meshheading:9609760-beta-Galactosidase
pubmed:year	1998
pubmed:articleTitle	The genetically programmed down-regulation of lactase in children.
pubmed:affiliation	Medical Research Council Human Biochemical Genetics Unit, University College London, England.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't