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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
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|
pubmed:dateCreated |
1998-7-27
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|
pubmed:abstractText |
Stanniocalcin (STC) is a mammalian polypeptide hormone that appears to play a role in mineral metabolism through its regulatory effects on renal phosphate transport. In this report we have characterized tissue-derived STC in humans and found it to be a glycosylated, disulfide-linked dimer, with similar physical and chemical properties to baculovirus-expressed hormone. The hormone was localized to principal and alpha-intercalated cells in the distal half of the nephron. This is the first homologous demonstration of STC proteins and cells in human tissue.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
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|
pubmed:issn |
0303-7207
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
137
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
155-9
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:9605517-Baculoviridae,
pubmed-meshheading:9605517-Blotting, Western,
pubmed-meshheading:9605517-Dimerization,
pubmed-meshheading:9605517-Disulfides,
pubmed-meshheading:9605517-Female,
pubmed-meshheading:9605517-Glycoproteins,
pubmed-meshheading:9605517-Hormones,
pubmed-meshheading:9605517-Humans,
pubmed-meshheading:9605517-Immunohistochemistry,
pubmed-meshheading:9605517-Kidney,
pubmed-meshheading:9605517-Male,
pubmed-meshheading:9605517-Nephrons,
pubmed-meshheading:9605517-Protein Conformation,
pubmed-meshheading:9605517-Recombinant Proteins
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|
pubmed:year |
1998
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|
pubmed:articleTitle |
Immunolocalization of stanniocalcin in human kidney.
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|
pubmed:affiliation |
Department of Physiology, Faculty of Dentistry and Medicine, University of Western Ontario, London, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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