Linked Life Data

9602480

Source:http://linkedlifedata.com/resource/pubmed/id/9602480

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-7-17
pubmed:abstractText
Recent reports suggest an increased incidence of chromosomal abnormalities in pregnancies with amniotic fluid-cell culture failure. We retrospectively reviewed the cytogenetic results of 14,165 amniotic fluid samples processed in our laboratory from 1987 to 1996. Ninety-eight per cent of the samples were obtained before 24 weeks' gestation, mainly because of advanced maternal age; 2 per cent were obtained after or at 24 weeks because of the ultrasonographic finding of fetal structural defects. Amniotic-fluid-cell culture failure occurred in 62 cases (0.44 per cent). Culture failure was more common in samples obtained after or at 24 weeks' gestation (10 per cent) than in those obtained before 24 weeks (0.27 per cent) (P < 0.001, chi-square test). This difference was also observed when the results were analysed according to the cases with known normal or abnormal karyotypes. The frequency of culture failure did not differ significantly between the groups with normal and abnormal karyotypes. We conclude that amniotic-fluid-cell culture failure is more common in advanced pregnancy with an ultrasonographic finding of fetal structural defects and is not associated with a higher incidence of chromosomal abnormalities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0197-3851
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Clinical significance of amniotic-fluid-cell culture failure.
pubmed:affiliation
Department of Obstetrics and Gynaecology, University of Hong Kong, Tsan Yuk Hospital, Hong Kong.
pubmed:publicationType
Journal Article