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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1998-7-23
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pubmed:abstractText |
A patient with a stage II seminoma of the testis was treated with a routine orchidectomy and irradiation. One and a half years later enlarged mediastinal lymph nodes were noted. Additional staging showed no other abnormalities and a mediastinoscopy was performed. The initial histologic examination confirmed the clinically suspected diagnosis of sarcoidosis. However, additional immunohistochemical analysis unexpectedly demonstrated that there was also a microscopic relapse of the testis tumor. The literature concerning the co-incidence of non-caseating granulomas and testis tumors is reviewed. It is not clear, whether the granulomas indicate the presence of genuine idiopathic sarcoidosis or whether they reflect a sarcoid-like reaction against tumor antigens. The immunopathogenesis of sarcoid formation and its possible biologic significance in obtaining a spontaneous tumor remission is discussed.
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pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0923-7534
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
321-5
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:9602267-Adult,
pubmed-meshheading:9602267-Antineoplastic Agents,
pubmed-meshheading:9602267-Diagnosis, Differential,
pubmed-meshheading:9602267-Disease-Free Survival,
pubmed-meshheading:9602267-Humans,
pubmed-meshheading:9602267-Immunohistochemistry,
pubmed-meshheading:9602267-Lymphatic Metastasis,
pubmed-meshheading:9602267-Male,
pubmed-meshheading:9602267-Mediastinal Diseases,
pubmed-meshheading:9602267-Mediastinoscopy,
pubmed-meshheading:9602267-Orchiectomy,
pubmed-meshheading:9602267-Sarcoidosis,
pubmed-meshheading:9602267-Seminoma,
pubmed-meshheading:9602267-Testicular Neoplasms,
pubmed-meshheading:9602267-Tomography, X-Ray Computed
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pubmed:year |
1998
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pubmed:articleTitle |
Coincidence of seminoma and sarcoidosis: a myth or fact?
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pubmed:affiliation |
Department of Medical Oncology, University Hospital Nijmegen, the Netherlands.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
|