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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
|
pubmed:dateCreated |
1998-8-3
|
pubmed:abstractText |
The nuclear envelope has a relatively small volume, but is connected up to the vastly larger endoplasmic reticulum. The Ca2+ concentration in the lumen of the interconnected nuclear envelope and endoplasmic reticulum network is in the resting state maintained at a level of more than 100 microM. There are specific Ca2+ release channels present in the inner nuclear membrane that can be activated by inositol trisphosphate or cADP ribose. The system, therefore, allows selective release of Ca2+ into the nucleoplasm which could be important for the control of specific types of gene expression.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0143-4160
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
87-90
|
pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9601603-Animals,
pubmed-meshheading:9601603-Biological Transport,
pubmed-meshheading:9601603-Calcium,
pubmed-meshheading:9601603-Calcium Channels,
pubmed-meshheading:9601603-Calcium-Transporting ATPases,
pubmed-meshheading:9601603-Endoplasmic Reticulum,
pubmed-meshheading:9601603-Nuclear Envelope
|
pubmed:articleTitle |
The calcium store in the nuclear envelope.
|
pubmed:affiliation |
MRC Secretory Control Research Group, Physiological Laboratory, University of Liverpool, UK.
|
pubmed:publicationType |
Journal Article,
Review
|