Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1998-6-11
pubmed:abstractText
Color vision was evaluated in twenty-one mercury exposed workers and referents matched for sex, age, tobacco smoking, and alcohol habits. The Lanthony 15 Hue desaturated panel (D-15 d) was applied. In the workers, mean urinary Hg (HgU) was 115+/-61.5 microg/g creatinine; in all but one the values exceeded the biological limit (BEI) proposed by the American Conference of Governmental Industrial Hygienists. A dose-related subclinical color vision impairment was observed in Hg-exposed workers compared to the referents. Just after the survey, working conditions were improved. Twelve months later the workers were reexamined. Mean HgU was 10.0 microg/g creatinine and in no subjects was the BEI exceeded. Color perception was significantly improved compared to the first examination and, furthermore, no differences were observed between exposed workers and referents. The results add evidence that the color vision loss observed during the first part of the study was related to Hg exposure and, moreover, show that this effect is reversible. These data indicate that metallic Hg can induce a reversible impairment in color perception. This suggests that color vision testing should be included in studies on the early effects of Hg. The possibility of applying the D-15 d as an early effect index in the biological monitoring of Hg exposed workers should also be entertained.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0013-9351
pubmed:author
pubmed:copyrightInfo
Copyright 1998 Academic Press.
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9600811-Adult, pubmed-meshheading:9600811-Case-Control Studies, pubmed-meshheading:9600811-Color Perception, pubmed-meshheading:9600811-Color Perception Tests, pubmed-meshheading:9600811-Color Vision Defects, pubmed-meshheading:9600811-Dose-Response Relationship, Drug, pubmed-meshheading:9600811-Environmental Pollutants, pubmed-meshheading:9600811-Female, pubmed-meshheading:9600811-Health Surveys, pubmed-meshheading:9600811-Humans, pubmed-meshheading:9600811-Male, pubmed-meshheading:9600811-Mercury, pubmed-meshheading:9600811-Mercury Poisoning, pubmed-meshheading:9600811-Methylmercury Compounds, pubmed-meshheading:9600811-Multivariate Analysis, pubmed-meshheading:9600811-Occupational Exposure, pubmed-meshheading:9600811-Regression Analysis, pubmed-meshheading:9600811-Time Factors, pubmed-meshheading:9600811-Vision, Low, pubmed-meshheading:9600811-Visual Acuity
pubmed:year
1998
pubmed:articleTitle
Reversible color vision loss in occupational exposure to metallic mercury.
pubmed:affiliation
Sezione di Medicina Preventiva dei Lavoratori, Università di Pavia, Pavia, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't