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rdf:type |
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lifeskim:mentions |
umls-concept:C0005767,
umls-concept:C0011306,
umls-concept:C0017262,
umls-concept:C0021757,
umls-concept:C0021759,
umls-concept:C0023516,
umls-concept:C0080091,
umls-concept:C0185117,
umls-concept:C0205100,
umls-concept:C0205214,
umls-concept:C2911684
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1998-6-4
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|
pubmed:abstractText |
IL-3, IL-5, and granulocyte-macrophage colony-stimulating factor (GM-CSF) receptors consist of cytokine-specific alpha-subunits, which associate with a shared signalling common beta-subunit (beta(c)) to form a high-affinity complex. The expression of IL-3, IL-5, and GM-CSF is upregulated in atopic inflammation, and these cytokines are thought to contribute to pathology through mechanisms that include eosinophil activation.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0091-6749
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
677-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9600506-Adolescent,
pubmed-meshheading:9600506-Adult,
pubmed-meshheading:9600506-Animals,
pubmed-meshheading:9600506-CHO Cells,
pubmed-meshheading:9600506-Cricetinae,
pubmed-meshheading:9600506-Dendritic Cells,
pubmed-meshheading:9600506-Female,
pubmed-meshheading:9600506-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:9600506-Humans,
pubmed-meshheading:9600506-Hypersensitivity, Immediate,
pubmed-meshheading:9600506-Leukocytes,
pubmed-meshheading:9600506-Male,
pubmed-meshheading:9600506-Mice,
pubmed-meshheading:9600506-Mice, Inbred BALB C,
pubmed-meshheading:9600506-Middle Aged,
pubmed-meshheading:9600506-Receptors, Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:9600506-Receptors, Interleukin,
pubmed-meshheading:9600506-Receptors, Interleukin-3,
pubmed-meshheading:9600506-Receptors, Interleukin-5
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pubmed:year |
1998
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|
pubmed:articleTitle |
IL-3, IL-5, granulocyte-macrophage colony-stimulating factor receptor alpha-subunit, and common beta-subunit expression by peripheral leukocytes and blood dendritic cells.
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|
pubmed:affiliation |
Allergy and Clinical Immunology, Imperial College School of Medicine at the National Heart and Lung Institute, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
