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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1998-6-1
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pubmed:abstractText |
The clinical course of 37 Enterocytozoon bieneusi-infected acquired immunodeficiency syndrome patients with diarrhea was studied. Parasite clearance was seen in 15 patients (40.5%). Clearance of E. bieneusi resulted in a 25-100% reduction in episodes of diarrhea, suggesting that microsporidia are true pathogens. Univariate and multivariate proportional hazards analyses revealed that peripheral blood CD4 cell counts > or = 100/mm3, the use of two or more antiretroviral medications, and use of a protease inhibitor were statistically associated with decreased time to clearance of E. bieneusi. Specific anti-microsporidial therapy (albendazole) was not associated with parasite eradication. Factors related to immunocompetence and human immunodeficiency virus suppression appeared to be important in the clearance of E. bieneusi.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0002-9637
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
555-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9598440-AIDS-Related Opportunistic Infections,
pubmed-meshheading:9598440-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:9598440-Adult,
pubmed-meshheading:9598440-Analysis of Variance,
pubmed-meshheading:9598440-Animals,
pubmed-meshheading:9598440-Anti-HIV Agents,
pubmed-meshheading:9598440-Humans,
pubmed-meshheading:9598440-Immunocompromised Host,
pubmed-meshheading:9598440-Intestinal Diseases, Parasitic,
pubmed-meshheading:9598440-Male,
pubmed-meshheading:9598440-Microsporida,
pubmed-meshheading:9598440-Microsporidiosis,
pubmed-meshheading:9598440-Middle Aged,
pubmed-meshheading:9598440-Protease Inhibitors,
pubmed-meshheading:9598440-RNA, Viral
|
pubmed:year |
1998
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pubmed:articleTitle |
Modification of the clinical course of intestinal microsporidiosis in acquired immunodeficiency syndrome patients by immune status and anti-human immunodeficiency virus therapy.
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pubmed:affiliation |
Division of Gastroenterology, Southern California Permanente Medical Group, Los Angeles 90027, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|