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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1998-6-30
|
| pubmed:abstractText |
The retroperitoneoscopic approach offers an established operative procedure for primary adrenal gland tumors. It allows a detailed view of the adrenal gland and its surrounding region. Therefore clear differentiation between normal and neoplastic adrenal tissue is sometimes possible, permitting a planned, unilateral, subtotal resection of the gland. Between July 1994 and August 1997 primary benign adrenal gland tumors (11 Conn adenomas, 4 phenochromocytomas, 4 Cushing adenomas, 3 hormonally inactive tumors; 2.4 +/- 1.2 cm in size; 8 on the right, 14 on the left) were removed from 22 patients by the posterior retroperitoneoscopic approach maintaining tumor-free portions of the ipsilateral adrenal gland. Two patients suffered from bilateral pheochromocytomas associated with multiple endocrine neoplasia (MEN-IIa) syndrome and had previously undergone complete adrenalectomy of the contralateral gland. Following subtotal resection the operating time and blood loss did not differ significantly (p > 0.05) from that seen with complete extirpation (46 patients operated during the same period). All patients with Conn adenomas and pheochromocytomas were biochemically and clinically cured (follow-up 11 months; range 1-31 months). The four patients with Cushing adenoma currently require decreasing cortisol substitution. In the two MEN-II patients adrenal gland cortical function could be maintained; one patient is on low-dose steroid supplementation and the other on none. No local recurrence of tumors has been observed. In selected cases the retroperitoneoscopically performed subtotal adrenal gland resection is a safe procedure that can potentially maintain the function of the adrenal gland cortex.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0364-2313
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
621-6; discussion 626-7
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9597938-Adolescent,
pubmed-meshheading:9597938-Adrenal Gland Neoplasms,
pubmed-meshheading:9597938-Adrenalectomy,
pubmed-meshheading:9597938-Adult,
pubmed-meshheading:9597938-Aged,
pubmed-meshheading:9597938-Child,
pubmed-meshheading:9597938-Female,
pubmed-meshheading:9597938-Humans,
pubmed-meshheading:9597938-Laparoscopy,
pubmed-meshheading:9597938-Male,
pubmed-meshheading:9597938-Middle Aged,
pubmed-meshheading:9597938-Multiple Endocrine Neoplasia Type 2a,
pubmed-meshheading:9597938-Pheochromocytoma,
pubmed-meshheading:9597938-Prospective Studies,
pubmed-meshheading:9597938-Retroperitoneal Space
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Subtotal adrenalectomy by the posterior retroperitoneoscopic approach.
|
| pubmed:affiliation |
Department of General Surgery, Medical School, University of Essen, Germany.
|
| pubmed:publicationType |
Journal Article
|