Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1998-5-22
|
| pubmed:abstractText |
The authors investigated risk profiles of sudden infant death syndrome (SIDS) as a function of age at death. A case-control study carried out in the Tyrol region of Austria enrolled 99 infants who died of SIDS between 1984 and 1994 and 136 randomly selected controls. Early and late SIDS (< 120 days of age vs. > or = 120 days) were defined according to the clear-cut bimodal age-at-death distribution. Inadequate antenatal care, low parental social and educational level, and the prone sleeping position were risk conditions that applied to both early and late SIDS. A marked seasonal variation (winter preponderance) was the most outstanding feature of late SIDS. A gestational age of < 37 weeks (odds ratio (OR) = 8.4, 95% confidence interval (CI) 2.6-26.0), repeated episodes of apnea (OR = 5.7, 95% CI 1.2-27.0), low birth weight (< 2,500 g) (OR = 3.4, 95% CI 1.1-11.0), a family history of sudden infant death (OR = 2.9, 95% CI 1.1-7.5), and maternal smoking during pregnancy (OR = 2.2, 95% CI 1.0-4.5) were associated with early SIDS. This study identified two distinct subgroups of SIDS infants characterized by different risk conditions and ages at death. These results underline a multiple-cause hypothesis for SIDS etiology which involves a genetic predisposition, immaturity in the first months of life, and environmental factors acting at various ages.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0002-9262
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
147
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
960-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9596474-Adult,
pubmed-meshheading:9596474-Austria,
pubmed-meshheading:9596474-Autopsy,
pubmed-meshheading:9596474-Birth Certificates,
pubmed-meshheading:9596474-Chi-Square Distribution,
pubmed-meshheading:9596474-Female,
pubmed-meshheading:9596474-Humans,
pubmed-meshheading:9596474-Infant,
pubmed-meshheading:9596474-Infant, Newborn,
pubmed-meshheading:9596474-Logistic Models,
pubmed-meshheading:9596474-Male,
pubmed-meshheading:9596474-Maternal Age,
pubmed-meshheading:9596474-Multivariate Analysis,
pubmed-meshheading:9596474-Prevalence,
pubmed-meshheading:9596474-Prone Position,
pubmed-meshheading:9596474-Questionnaires,
pubmed-meshheading:9596474-Random Allocation,
pubmed-meshheading:9596474-Risk Factors,
pubmed-meshheading:9596474-Seasons,
pubmed-meshheading:9596474-Sex Distribution,
pubmed-meshheading:9596474-Sleep,
pubmed-meshheading:9596474-Sudden Infant Death,
pubmed-meshheading:9596474-Survival Rate
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Sudden infant death syndrome: risk factor profiles for distinct subgroups.
|
| pubmed:affiliation |
Department of Pediatrics, University Hospital of Innsbruck, Austria.
|
| pubmed:publicationType |
Journal Article
|