Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1998-6-5
|
pubmed:abstractText |
Electron microscopy immunocytochemical study was performed to clarify ultrastructural localization and role of endothelial nitric oxide synthase (EC-NOS) in the endothelial cells (EC) of rat hippocampal vessels after transient cerebral ischemia. EC-NOS immunoreactivity was found in the endothelial cells in association with plasma membrane, sub-plasmalemmal vesicles, basal membrane and in cytosol (cytoplasm free of subcellular organelles). A sharp transient increase in immunoreactivity of NOS was observed at 10 min up to 1 hour after ischemia. The results of the present study indicate that NO, as a potent vasodilator, may play a protective role in ischemic brain damage.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1641-4640
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
171-80
|
pubmed:dateRevised |
2005-11-17
|
pubmed:meshHeading |
pubmed-meshheading:9595852-Animals,
pubmed-meshheading:9595852-Cell Membrane,
pubmed-meshheading:9595852-Cytoplasm,
pubmed-meshheading:9595852-Cytosol,
pubmed-meshheading:9595852-Endothelium, Vascular,
pubmed-meshheading:9595852-Hippocampus,
pubmed-meshheading:9595852-Immunohistochemistry,
pubmed-meshheading:9595852-Ischemic Attack, Transient,
pubmed-meshheading:9595852-Male,
pubmed-meshheading:9595852-Nitric Oxide Synthase,
pubmed-meshheading:9595852-Organelles,
pubmed-meshheading:9595852-Rats,
pubmed-meshheading:9595852-Rats, Wistar
|
pubmed:year |
1997
|
pubmed:articleTitle |
Endothelial nitric oxide synthase in vascular endothelium of rat hippocampus after ischemia: evidence and significance.
|
pubmed:affiliation |
Laboratory of the Ultrastructure of the Nervous System, Polish Academy of Sciences, Warszawa.
|
pubmed:publicationType |
Journal Article
|