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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-5-28
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pubmed:abstractText |
In 1990, to study regional prevalences and risk factors of Helicobacter pylori infection in healthy young adult males, sera were collected from a nationwide sample of 1659 males (mean age 20.7 years) at introduction into the Air Force School for military students in Caserta, Italy. An enzyme-linked immunosorbent assay was used to detect H. pylori specific immunoglobulin G antibodies. The observed overall seropositivity rate was 17.5% (95% CI 15.7-19.4). Prevalence was higher in southern Italy and in the Italian islands as compared with northern Italy and central Italy (21.3% vs. 9.5%). Multiple logistic regression analysis showed that residence in southern areas and islands was the strongest predictor of the likelihood of H. pylori seropositivity; number of siblings in the household was marginally associated; years of father's schooling was not a significant predictor. H. pylori positive subjects were more likely positive for antibodies to hepatitis A virus infection (anti-HAV) than those H. pylori negative (35.4% vs. 24.9%; Odds Ratio 1.7, 95% CI 1.3-2.2). Adjustment for the confounding effect of sociodemographic variables weakened this association (OR 1.3, 95% CI 1.0-1.7). These findings suggest that differences in environmental conditions rather than in socioeconomic status may have played the major role in the different spread of H. pylori infection across the country.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0950-2688
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-5
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pubmed:dateRevised |
2010-3-3
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pubmed:meshHeading |
pubmed-meshheading:9593484-Adult,
pubmed-meshheading:9593484-Comorbidity,
pubmed-meshheading:9593484-Helicobacter Infections,
pubmed-meshheading:9593484-Helicobacter pylori,
pubmed-meshheading:9593484-Hepatitis A Antibodies,
pubmed-meshheading:9593484-Hepatitis Antibodies,
pubmed-meshheading:9593484-Humans,
pubmed-meshheading:9593484-Italy,
pubmed-meshheading:9593484-Logistic Models,
pubmed-meshheading:9593484-Male,
pubmed-meshheading:9593484-Military Personnel,
pubmed-meshheading:9593484-Odds Ratio,
pubmed-meshheading:9593484-Population Surveillance,
pubmed-meshheading:9593484-Predictive Value of Tests,
pubmed-meshheading:9593484-Prevalence,
pubmed-meshheading:9593484-Risk Factors,
pubmed-meshheading:9593484-Seroepidemiologic Studies,
pubmed-meshheading:9593484-Socioeconomic Factors,
pubmed-meshheading:9593484-Students
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pubmed:year |
1998
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pubmed:articleTitle |
Prevalence of Helicobacter pylori infection in a cohort of Italian military students.
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pubmed:affiliation |
Istituto Superiore di Sanità, Laboratorio di Epidemiologia e Biostatistica, Roma.
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pubmed:publicationType |
Journal Article
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