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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1998-6-15
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pubmed:abstractText |
Nitric oxide is considered to be the most important messenger of inhibitory nonadrenergic, noncholinergic nerves in the enteric nervous system. Histochemical studies have shown that nitric oxide synthase is identical to reduced nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase. Histochemical staining with NADPH diaphorase has been widely used to study nitrergic innervation of the gastrointestinal tract, but fresh tissue is considered a prerequisite for satisfactory results. The purposes of this study were to evaluate whether whole-mount specimens of human bowel obtained after death are suitable for histochemical staining with NADPH diaphorase and to compare the staining properties with those of specimens of resected bowel from patients with Hirschsprung's disease
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0003-9985
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
461-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9593349-Child,
pubmed-meshheading:9593349-Child, Preschool,
pubmed-meshheading:9593349-Hirschsprung Disease,
pubmed-meshheading:9593349-Histocytochemistry,
pubmed-meshheading:9593349-Humans,
pubmed-meshheading:9593349-Infant,
pubmed-meshheading:9593349-Infant, Newborn,
pubmed-meshheading:9593349-Myenteric Plexus,
pubmed-meshheading:9593349-NADPH Dehydrogenase,
pubmed-meshheading:9593349-Nerve Fibers,
pubmed-meshheading:9593349-Neurons,
pubmed-meshheading:9593349-Postmortem Changes,
pubmed-meshheading:9593349-Time Factors,
pubmed-meshheading:9593349-Tissue Fixation
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pubmed:year |
1998
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pubmed:articleTitle |
NADPH diaphorase-containing nerve fibers and neurons in the myenteric plexus are resistant to postmortem changes: studies in Hirschsprung's disease and normal autopsy material.
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pubmed:affiliation |
Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin, Ireland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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