rdf:type |
|
lifeskim:mentions |
umls-concept:C0009491,
umls-concept:C0017262,
umls-concept:C0032112,
umls-concept:C0085663,
umls-concept:C0178650,
umls-concept:C0185117,
umls-concept:C0205332,
umls-concept:C0376515,
umls-concept:C1579762,
umls-concept:C1709160,
umls-concept:C2911684
|
pubmed:issue |
4
|
pubmed:dateCreated |
1998-6-24
|
pubmed:abstractText |
bcl-2 oncoprotein plays a major physiological role in hemopoietic and non-hemopoietic cells by preventing apoptosis (programmed cell death). Disregulation of this process may be important in oncogenesis and the response to treatment of patients with different hematological malignancies. We have investigated the levels of bcl-2 expression in plasma cells from patients with reactive plasmacytosis (RP), monoclonal gammopathy of unknown significance (MGUS) and multiple myeloma (MM), correlating the bcl-2 expression and clinico-biological features in MM patients.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0390-6078
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
298-304
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9592978-Adult,
pubmed-meshheading:9592978-Aged,
pubmed-meshheading:9592978-Aged, 80 and over,
pubmed-meshheading:9592978-Female,
pubmed-meshheading:9592978-Hematologic Neoplasms,
pubmed-meshheading:9592978-Humans,
pubmed-meshheading:9592978-Lymphocytosis,
pubmed-meshheading:9592978-Male,
pubmed-meshheading:9592978-Middle Aged,
pubmed-meshheading:9592978-Multiple Myeloma,
pubmed-meshheading:9592978-Paraproteinemias,
pubmed-meshheading:9592978-Plasma Cells,
pubmed-meshheading:9592978-Prognosis,
pubmed-meshheading:9592978-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:9592978-Survival Rate,
pubmed-meshheading:9592978-Treatment Outcome
|
pubmed:year |
1998
|
pubmed:articleTitle |
bcl-2 expression in plasma cells from neoplastic gammopathies and reactive plasmacytosis: a comparative study.
|
pubmed:affiliation |
Service of Hematology, Valencia University General Hospital, Spain.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|